Why We Need Retinol Alternative Skincare

Written by: Dr Tiina Meder

|

Published on

|

Last updated on

|

Time to read 3 min

Dr Tiina Meder

Dr Tiina Meder

Founder and CEO of Meder by Dr Tiina Meder (founded in 2009), dermatologist and cosmetic safety expert, an experienced lecturer and speaker on the topic of dermatology and skin care, sharing her expertise around the world in Japan, Taiwan, IMCAS Europe and China, FACE, CCR, APAN (Australia, New Zealand), LNE (France, Poland, Ukraine) and Microbiome Connection (USA) to name but a few. Across her career she has had more than 50 articles published. 

Retinol is one of the most celebrated ingredients in skincare, renowned for its ability to smooth skin texture, even tone, and combat signs of aging. However, despite its popularity and effectiveness, retinol is not without controversy. Many users experience side effects such as irritation and sensitivity, and there are important health considerations, especially for pregnant or breastfeeding women.

With recent regulatory changes and growing awareness of retinol’s limitations, the skincare world is embracing gentle, effective retinol alternatives. These innovative ingredients offer similar benefits without the harsh side effects, making them ideal for sensitive skin and those seeking safer options.

The Science Behind Retinol and Its Challenges

Retinol, also known as vitamin A, plays a vital role in skin renewal and overall health. It regulates cell turnover and supports the differentiation and proliferation of cells throughout the body. This is why retinoids are so effective in promoting youthful, radiant skin.


However, retinol’s active form, retinoic acid, is naturally produced by the body in very small amounts, ensuring a smooth and gentle renewal process. When applied topically in higher concentrations, retinol accelerates skin renewal, which can lead to redness, irritation, and a condition known as retinoic dermatitis.


Moreover, retinol is chemically unstable and breaks down under ultraviolet (UV) light, generating free radicals that increase oxidative stress and sun sensitivity. This makes daytime use risky and necessitates strict sun protection

New European Regulations on Retinol

Due to these concerns, the European Union has taken significant steps to regulate retinol use in cosmetics. As of 2022, retinoic acid is banned in skincare products, and limits have been set on retinol concentrations. From November 2025, products containing retinol and certain derivatives will no longer be available in the EU market, with other countries likely to follow.


These regulations highlight the urgent need for safe, effective retinol alternatives.

Why Choose Retinol Alternatives?

Retinol alternatives provide many advantages:

  • They reduce the risk of irritation and sensitivity.
  • They are safer for use during pregnancy and breastfeeding.
  • They don't have the instability and sun sensitivity issues of retinol.
  • They offer comparable benefits in improving skin texture, tone, and signs of ageing.

Top Retinol Alternatives in Skincare

Several natural and biotechnological ingredients have emerged as effective retinol alternatives:

  • Avocutine. Derived from virgin avocado oil, it reduces sebum production and inflammation, making it excellent for oily and acne-prone skin.
  • Maclura Plant Bioflavonoids. Used in traditional Southeast Asian medicine, this extract regulates sebum and stimulates collagen, helping with acne and aging.
  • Bakuchiol. A well-known plant-based alternative that boosts collagen and improves skin elasticity without irritation.
  • Siliphos. Extracted from milk thistle, it supports collagen synthesis and skin elasticity.
  • Vit-A-Like. Derived from moth beans, it promotes skin renewal and improves texture.
  • Nephoria. From rambutan fruit, it enhances collagen and elastin production.
  • Halorubin. A biotechnological antioxidant protecting against UV damage and premature aging.
  • Novoretin. Derived from mastic gum, it inhibits retinoic acid breakdown, improving skin elasticity and moisture.

What Makes a Retinol Alternative?

Retinol alternatives either mimic retinoid effects or support the skin’s natural retinoic acid levels. Many innovative ingredients also offer anti-aging benefits through peptides, growth factors, stem cells, and antioxidants, often with better tolerance and safety profiles.

Meder’s Commitment to Safe, Inclusive Skincare

At Meder, we have never used retinol or its derivatives in our formulations. Safety and inclusivity, especially for pregnant and breastfeeding women, have been core values since our inception.

The Future of Skincare is Gentle and Effective

With growing scientific understanding and regulatory changes, retinol alternatives are becoming the new standard for safe, effective skincare. They offer the benefits of retinoids without the drawbacks, making them suitable for all skin types and life stages.


Explore Meder’s range of retinol alternative products and embrace a skincare routine that respects your skin’s health and your overall wellbeing.

Cart (${ cart.item_count })